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Illudin M
CAS No. 1146-04-9
Illudin M ( —— )
产品货号. M34856 CAS No. 1146-04-9
Illudin M 是一种细胞毒性真菌倍半萜，可以从 Omphalotus illudens 蘑菇培养基中分离得到的。Illudin M 能使 DNA 烷基化。Illudin M 具有抗肿瘤活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥5336 | 有现货 |
|
| 5MG | ￥7009 | 有现货 |
|
| 10MG | ￥11224 | 有现货 |
|
| 25MG | ￥15484 | 有现货 |
|
| 50MG | ￥21740 | 有现货 |
|
| 100MG | ￥28764 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Illudin M
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Illudin M 是一种细胞毒性真菌倍半萜，可以从 Omphalotus illudens 蘑菇培养基中分离得到的。Illudin M 能使 DNA 烷基化。Illudin M 具有抗肿瘤活性。
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产品描述Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus illudens mushrooms. Illudin M can alkylate DNA. Illudin M has anti-tumor activities.
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体外实验Illudin M (0.01-10 μM; 24-120 hours) shows cytotoxicity and induction of apoptosis in vitro.Apoptosis Analysis Cell Line:Panc-1 pancreatic carcinoma, HT-29 colon adenocarcinoma, non-malignant human foreskin fibroblasts (HFs) Concentration:0.01 μM, 1 μM, 10 μM Incubation Time:24 hours, 48 hours,72 hours, 96 hours, 120 hours Result:Showed a comparable induction of apoptosis in the tumour cells (86% in Panc-1; 48% in HT-29), but an even greater one in the HF (89%).
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体DNA Alkylator/Crosslinker | Apoptosis
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研究领域——
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适应症——
化学信息
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CAS Number1146-04-9
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分子量248.32
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分子式C15H20O3
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1=C2[C@@H](O)C(C)(C)C=C2C(=O)[C@](C)(O)C11CC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Rainer Schobert, et al. Conjugates of the fungal cytotoxin illudin M with improved tumour specificity. Bioorg Med Chem. 2008 Sep 15;16(18):8592-7.?
